Fig. 5.
Melanoma cells show increased transcription of the IL-29 receptors. The cDNA of the mRNA of IL-10R2 and IL-28R1 were detected via in situ PCR amplification. Benign nevi were negative for IL-10R2 and IL-28R1. Cytoplasmic signal for IL-10R2 and IL-28R1 were present in melanoma lesions but not in benign nevi. Magnification, 40x, scale bars = 25 microns. Left column, receptor staining. Right column, negative control.