Table 4.
H | BA | x | y | z | T | Voxels | |
met/met > val/vala | |||||||
ESA | |||||||
^Orbitofrontal cortex | L | 11 | −11 | 47 | −18 | 4.02 | 50 |
^Superior PFC | R | 6 | 11 | 11 | 66 | 3.43 | 43 |
^ACC | R | 24/32 | 15 | 16 | 27 | 3.24 | 41 |
^Dorsolateral PFC | R | 10/46 | 41 | 41 | 12 | 3.28 | 30 |
^Sensorimotor cortex | L | 4/6 | −26 | −9 | 46 | 3.61 | 85 |
Insula | R | 13 | 38 | −7 | 14 | 3.59 | 79 |
Superior temporal gyrus | R | 21/22 | 56 | −44 | −1 | 5.28 | 93 |
Temporal–parietal junction | L | 40/37/22/20 | −38 | −43 | 16 | 4.43 | 210 |
RSA | |||||||
^Dorsomedial PFC | R | 9/46 | 26 | 38 | 23 | 2.9 | 103 |
Putamen | R | 23 | 22 | 2 | 3.68 | 30 | |
^ACC | R | 24 | 19 | 29 | −5 | 3.42 | (10) |
Parietofrontal cortex | R | 40/7/39/31 | 30 | −54 | 31 | 5.49 | 506 |
^Superior PFC | R | 8/6 | 45 | 10 | 49 | 3.28 | (71) |
Thalamus | R | 19 | −19 | −5 | 2.97 | 50 | |
*Anterior PHG | R | 34 | 11 | −8 | −19 | 2.27 | (8) |
Retrosplenial cortex | M | 23 | 0 | −28 | 22 | 3.54 | 44 |
Occipital cortex | R | 18/19 | 23 | −85 | 8 | 3.21 | 38 |
Cerebellum | R | 23 | −31 | −30 | 2.85 | 34 | |
val/val>met/metb | |||||||
ESA | |||||||
Occipitotemporal cortex | L | 17/18/27/30 | −11 | −33 | −2 | 4.68 | 262 |
*PHG | L | 27/30 | −19 | −37 | −8 | 4.17 | (18) |
Posterior cingulate/occipital cortex | L | 18/19/20/30/35 | −11 | −36 | 23 | 3.38 | 204 |
*PHG | R | 35 | 19 | −30 | −11 | 2.84 | (13) |
Anterior temporal cortex | R | 28/34/38 | 26 | 10 | −23 | 4.57 | 67 |
*Rhinal cortex | R | 28/34 | 23 | −5 | −19 | 3.23 | (18) |
Anterior temporal cortex | L | 38/28/20 | −41 | 5 | −39 | 3.16 | 41 |
*Rhinal cortex | L | 38/20 | −26 | −1 | −22 | 2.26 | (6) |
ACC | R | 32/10 | 11 | 45 | 12 | 3.19 | 47 |
Caudate | L | −23 | 14 | −7 | 2.63 | 32 | |
Occipitoparietal cortex | R | 40013 | 15 | −53 | 45 | 4.06 | 78 |
Cerebellum | M | 0 | −50 | −33 | 3.98 | 84 | |
RSA | |||||||
*PHG/HC | L | 27/35 | −19 | −26 | −2 | 3.89 | 34 |
Superior/middle temporal gyrus | R | 22/42 | 49 | −25 | 15 | 4.31 | 186 |
*Rhinal cortex/PHG | R | 34 | 30 | 7 | −16 | 3.54 | (9) |
Superior temporal gyrus | L | 29 | −41 | −32 | 16 | 3.09 | 96 |
*Rhinal cortex/PHG | L | 34 | −30 | −4 | −13 | 1.87 | (4) |
Orbitofrontal cortex | L | 10/9 | −8 | 63 | 7 | 3.44 | 59 |
Posterior cingulate | L | 31 | −11 | −66 | 14 | 4.55 | 61 |
Inferior parietal cortex | L | 3 | −56 | −20 | 40 | 3.26 | 45 |
Cerebellum | L | −11 | −64 | −32 | 3.99 | 383 |
Brain regions exhibiting greater MTL connectivity during encoding and retrieval for individuals homozygous for the met allele compared with individual honogygous for the val allele.
Brain regions exhibiting greater MTL connectivity during encoding and retrieval for individuals homozygous for the val allele compared with individual honogygous for the met allele. Results include all significant group differences within the MTL and PFC significant at P < 0.05, with a minimum cluster size > 30 voxels. ESA: encoding success activity; RSA: retrieval success activity; PHG: parahippocampal gyrus; PFC: prefrontal cortex; ACC: anterior cingulate cortex; H: hemisphere; BA: Brodmann's area; ^highlights PFC regions; *highlights MTL regions; brackets () indicate the voxel extent of the subpeaks, which are identified through the use of indentations in the table.