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. 1999 Aug 28;319(7209):550–553. doi: 10.1136/bmj.319.7209.550

Table 2.

Percentage of patients achieving adequate control of heartburn in each treatment arm during week before 2, 4, and 8 week visits

Visit Placebo (n=159) Cisapride (n=163) Omeprazole (n=161) P value*
2 weeks 15 21 59 <0.0001
4 weeks (95% CI) 18 (12.0 to 24.4) 22 (15.4 to 28.6) 71 (63.8 to 78.4) <0.0001
8 weeks 30 40 76 <0.0001

Six patients who were prematurely withdrawn but reported adequate control of heartburn are included: omeprazole (3), cisapride (2), placebo (1). 

*

Omeprazole v cisapride or placebo.