Table 3.

Proportion of patients achieving adequate control of heartburn, mean number of days per week with heartburn after 2, 4, and 8 weeks of treatment, and median number of antacid tablets consumed

Variable	Placebo (n=159)	Cisapride (n=163)	Omeprazole (n=161)	P value†
Patients (%) achieving adequate control of heartburn*
2 weeks	15	21	59
4 weeks	18	22	71	<0.0001
8 weeks	30	40	76
Mean No of days per week with heartburn
Baseline	5.5	5.4	5.7	<0.001
2 weeks	4.3	3.6	1.8
4 weeks	3.9	3.4	1.2
8 weeks	3.5	3.0	1.0
Median No of antacid tablets consumed
Weeks 1-2	13	9	2
Weeks 3-4	10	8	0	<0.0001
Weeks 5-8	17	12	0

^*No more than mild heartburn for ⩽1 day per week. 

^†Omeprazole v cisapride or placebo.