TABLE 1.
Electrophysiological properties of AQP1+/+ and AQP1−/− small DRG neurons
Differences are not significant. AHP, after-hyperpolarization.
Membrane potential | Input resistance | Cell capacitance | Injection current threshold | AP 50% width | AHP | |
---|---|---|---|---|---|---|
mV | Gigaohms | Picofarads | nA | ms | mV | |
AQP1+/+ | −62.7 ± 1.0 (n = 45) | 1.3 ± 0.1 (n = 45) | 18.7 ± 0.7 (n = 45) | 0.6 ± 0.1 (n = 26) | 3.4 ± 0.4 (n = 26) | 12.3 ± 1.2 (n = 26) |
AQP1−/− | −62.9 ± 1.4 (n = 50) | 1.0 ± 0.1 (n = 50) | 17.6 ± 0.8 (n = 50) | 0.6 ± 0.1 (n = 28) | 3.3 ± 0.4 (n = 28) | 11.3 ± 1.0 (n = 28) |