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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Hypertension. 2009 Dec 28;55(2):562. doi: 10.1161/HYPERTENSIONAHA.109.145656

Figure 2.

Figure 2

Human renin (hREN) and angiotensinogen (hAGN) mRNA in the uteroplacental unit of normal pregnant (SD) and pregnant transgenics resulting from the mating of female hAGN × male hREN (preeclamptic model) and the reverse mating (RM). As expected, there is no hAGN or hREN mRNAs in SD placenta. In the preeclamptic model, both hREN and hAGN mRNAs are expressed in the MT and fetal Pla, although hREN mRNA shows a low level of expression in the MT. On the other hand, in the RM both mRNAs are expressed in the Pla, but hAGN is expressed at substantially lower levels in the MT compared to the preeclamptic model. Values are mean ± SEM. * p<0.01 between transgenic groups.