TABLE 2.
Amino acid substitutions in the A/2009 H1N1 influenza virus hemagglutinina
| GenBank accession no. | Isolate | Amino acid at positionb: |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HA1 |
HA2 |
|||||||||||||||
| 67 | 89 | 170 | 193 | 198 | 199 | 220 | 222 | 250 | 288 | 295 | 334 | 376 | 385 | 422 | ||
| GQ303340 | M 4487 | C | T | G | Q | Y | V | V | D | V | T | I | A | T | K | N |
| GQ369403 | Pig no. 1 (33-1) | R | - | - | - | - | - | - | - | - | A | - | - | - | - | - |
| GQ369406 | Pig no. 2 (33-2) | - | - | - | - | N | - | - | - | - | - | - | V | - | - | - |
| GQ369409 | Pig no. 3 (33-3) | - | - | E | - | - | - | - | V | I | - | - | - | A | - | - |
| GQ369412 | Pig no. 7 (33-7) | - | A | - | - | - | - | - | - | - | - | - | - | - | - | T |
| GQ369417 | Pig no. 21 (33-21) | R | - | - | - | - | A | M | - | - | - | V | - | - | - | - |
| GQ369422 | Pig no. 23 (33-23) | - | - | - | - | - | - | - | - | - | - | - | - | - | E | - |
| GQ369425 | Pig no. 24 (33-24) | - | - | - | H | - | - | M | - | - | - | - | - | - | - | - |
| GQ150328 | Pig no. 8 (33-8) | - | - | - | - | N | - | - | - | - | - | - | V | - | - | - |
a
Amino acid substitutions in the hemagglutinin protein of H1N1 viruses isolated from different pigs from barns D, E, and F as listed in Table 1 compared with the human isolate A/Mexico/InDRE/4487/2009 (H1N1). M 4487, isolate A/Mexico/InDRE/4487/09; isolates A 33-1, -2, -3, -7, -21, -23, and -24 are swine isolates from Alberta; A 33-8 is the isolate A/sw/Alberta/OTH-33-8/09. Isolates in the rows in boldface are those that were used in experimental-infection studies.
b
-, no substitution.