TABLE 5.
Amino acid substitutions in the A/2009 H1N1 influenza virus nucleoproteina
| GenBank accession no. | Isolate | Amino acid at positionb: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 35 | 49 | 107 | 136 | 198 | 208 | 228 | 295 | 379 | 381 | ||
| FJ998217 | M 4487 | V | D | D | T | E | N | M | H | T | D |
| GQ478577 | Pig no. 1 (33-1) | - | - | - | - | - | - | - | - | I | N |
| GQ478578 | Pig no. 2 (33-2) | - | E | - | I | - | - | - | - | I | - |
| GQ478579 | Pig no. 3 (33-3) | - | - | - | I | - | - | - | L | I | - |
| GQ478580 | Pig no. 14 (33-14) | - | - | - | - | - | - | - | - | I | - |
| GQ478581 | Pig no. 22 (33-22) | - | - | G | - | - | - | - | - | I | - |
| GQ478582 | Pig no. 23 (33-23) | - | - | - | - | - | - | - | - | I | - |
| GQ478583 | Pig no. 24 (33-24) | - | - | - | - | - | - | - | - | I | - |
| GQ150329 | Pig no. 8 (33-8) | A | - | - | - | K | D | T | - | I | Y |
a
Amino acid substitutions in the neuraminidase proteins of H1N1 viruses isolated from different pigs from barns D, E and F as listed in Table 1 compared with the human isolate A/Mexico/InDRE/4487/2009 (H1N1). M 4487, isolate A/Mexico/InDRE/4487/09; isolates A 33-1, -2, -3, -14, -22, -23, and -24 are swine isolates from Alberta; A 33-8 is the isolate A/sw/Alberta/OTH-33-8/09. Isolates in the rows in boldface are those that were used in experimental-infection studies.
b
-, no substitution.