Left and right hippocampal volumes (mean ± SEM) in control, high-risk and depressed groups (Significant differences in hippocampal volume after controlling for age, gender, ethnicity/race, pubertal status and socioeconomic status; Left: controls vs. high-risk, p = .0001; controls vs. depressed, p = .002; Right: controls vs. high-risk, p = .0001; controls vs. depressed, p = .005).