Table 5.

Association of individual markers of depression with Incident Hypertension (JNC7 definition; n=409) among 3130 participants in the Multi-Ethnic Study of Atherosclerosis between exam 1 and exam 2

Parameter	Relative Risk (RR)	Confidence Limits	P-value
Lightly adjusted model*
Baseline Tricyclic Antidepressant Use (n=38)	1.24	1.06 to 1.44	0.0065
Baseline non-Tricyclic Antidepressant Use (n=193)	1.02	0.96 to 1.08	0.5976
CESD Score (per unit) ‡	1.000	0.998 to 1.002	0.8840
Fully Adjusted Model†
Baseline Tricyclic Antidepressant Use (n=38)	1.20	1.05 to 1.37	0.0090
Baseline non-Tricyclic Antidepressant Use (n=193)	0.99	0.93 to 1.04	0.6282
CESD Score (per unit)‡	1.000	0.997 to 1.002	0.8071

^*adjusted for age, sex and ethnicity.

^†adjusted for age, sex, ethnicity, smoking, alcohol use, diabetes, body mass index, exercise (intentional and sedentary), Spielberger anxiety and anger scores, health insurance, income and baseline systolic and diastolic blood pressure

^‡Note that CESD is a continuous variable in this analysis and not a indicator of CES-D ≥ 16; the binary variable would also have tested as non-significant.