Table 1.
Characteristics of 311 endometrial cancer cases and 570 controls (nested within the California Teachers Study)
| Characteristics | Categories | Cases N (%) |
Controls N (%) |
P Value* |
|---|---|---|---|---|
| Age | <55 | 28 (9.0) | 54 (9.5) | |
| 55–59 | 58 (18.6) | 100 (17.5) | ||
| 60–64 | 63 (20.3) | 101 (17.7) | ||
| 65–69 | 54 (17.4) | 110 (19.3) | ||
| 70–74 | 55 (17.7) | 108 (18.9) | ||
| 75+ | 53 (17.0) | 97 (17.0) | ||
| Race | White | 300 (96.5) | 525 (92.1) | |
| African American | 2 (0.6) | 9 (1.6) | ||
| Hispanic | 3 (1.0) | 17 (3.0) | ||
| Other | 6 (1.9) | 19 (3.3) | ||
| Menopause Type | Natural | 205 (65.9) | 391 (68.6) | |
| First HT Use | 100 (32.2) | 167 (29.3) | ||
| Other | 6 (1.9) | 12 (2.1) | 0.75 | |
| Menopause Age | <47 | 55 (17.7) | 102 (17.9) | |
| 47–49 | 57 (18.3) | 125 (21.9) | ||
| 50–52 | 91 (29.3) | 192 (33.7) | ||
| 53–55 | 74 (23.8) | 115 (20.2) | ||
| 56+ | 34 (10.9) | 36 (6.3) | 0.033 | |
| Menarche Age | <12 | 64 (20.6) | 99 (17.4) | |
| 12 | 78 (25.1) | 162 (28.4) | ||
| 13 | 104 (33.4) | 180 (31.6) | ||
| 14+ | 65 (20.9) | 129 (22.6) | 0.58 | |
| BMI | <25 | 142 (45.7) | 336 (58.9) | |
| 25–29 | 93 (29.9) | 163 (28.6) | ||
| 30–34 | 48 (15.4) | 51 (8.9) | ||
| 35+ | 28 (9.0) | 20 (3.5) | <0.001 | |
| Parity | Nulliparous | 75 (24.1) | 108(18.9) | |
| Parous | 236 (75.9) | 462 (81.1) | 0.092 | |
|
Number of Full-Term Pregnancies |
0 | 75 (24.1) | 108 (18.9) | |
| 1 | 40 (12.9) | 70 (12.3) | ||
| 2 | 95 (30.5) | 173 (30.4) | ||
| 3 | 72 (23.2) | 145 (25.4) | ||
| 4+ | 29 (9.3) | 74 (13.0) | 0.19 | |
|
Age at Last full-Term Pregnancy† |
<25 | 25 (10.6) | 42 (9.1) | |
| 25–29 | 92 (39.0) | 149 (32.3) | ||
| 30–34 | 85 (36.0) | 178 (38.5) | ||
| 35+ | 34 (14.4) | 93 (20.1) | 0.053 | |
| OC Use | Never Use | 187 (60.1) | 298 (52.3) | |
| <5y | 69 (22.2) | 120 (21.1) | ||
| 5–9y | 37 (11.9) | 70 (12.3) | ||
| 10–14y | 9 (2.9) | 39 (6.8) | ||
| 15+y | 9 (2.9) | 43 (7.5) | <0.001 | |
*
Multivariate logistic regression models adjusted for matching factors (age, race, geographic area of residence, and reference year)
†
Additionally, adjusted for total number of full-term pregnancies
Abbreviations: BMI: Body Mass Index; OC: Oral Contraceptive