Table.
Association between characteristics of women and current use of hormone replacement therapy (HRT), with both crude and adjusted odds ratios
| Total No of women (n=865)* | No (%) of women using HRT | Odds ratio (95% CI)
|
||
|---|---|---|---|---|
| Crude | Adjusted† | |||
| Ethnic group: | ||||
| White | 282 | 70 (24.8) | 1 | 1 |
| African descent | 333 | 51 (15.3) | 0.55 (0.36 to 0.83) | 0.54 (0.35 to 0.83) |
| South Asian | 250 | 25 (10.0) | 0.32 (0.19 to 0.53) | 0.37 (0.22 to 0.63) |
| Hysterectomy‡: | ||||
| No | 821 | 132 (16.1) | 1 | 1 |
| Yes | 44 | 14 (31.8) | 2.44 (1.19 to 4.92) | 2.55 (1.28 to 5.10) |
| Current smoker: | ||||
| No | 738 | 113 (15.3) | 1 | 1 |
| Yes | 126 | 33 (26.2) | 1.96 (1.23 to 3.13) | 1.59 (0.97 to 2.60) |
| Age (years): | ||||
| <45 | 206 | 15 (7.3) | 1 | 1 |
| 45-49 | 219 | 35 (16.0) | 2.42 (1.23 to 4.82) | 2.64 (1.38 to 5.06) |
| 50-54 | 225 | 49 (21.8) | 3.55 (1.85 to 6.87) | 3.74 (2.00 to 7.00) |
| ⩾55 | 215 | 47 (21.9) | 3.56 (1.85 to 6.93) | 4.02 (2.14 to 7.56) |
| Hypertension‡: | ||||
| No | 568 | 93 (16.4) | 1 | 1 |
| Yes | 295 | 53 (18.0) | 1.12 (0.76 to 1.65) | 1.09 (0.73 to 1.64) |
| Diabetes mellitus‡: | ||||
| No | 799 | 138 (17.3) | 1 | 1 |
| Yes | 65 | 8 (12.3) | 0.67 (0.29 to 1.50) | 0.69 (0.31 to 1.53) |
| High cholesterol‡: | ||||
| No | 792 | 128 (16.2) | 1 | 1 |
| Yes | 69 | 17 (24.6) | 1.70 (0.91 to 3.13) | 1.44 (0.78 to 2.65) |
| Ischaemic heart disease‡: | ||||
| No | 836 | 138 (16.5) | 1 | 1 |
| Yes | 29 | 8 (27.6) | 1.93 (0.77 to 4.70) | 1.40 (0.58 to 3.34) |
| Cardiovascular risk§: | ||||
| No | 507 | 79 (15.6) | 1 | 1 |
| Yes | 358 | 67 (18.7) | 1.25 (0.86 to 1.81) | 1.17 (0.79 to 1.72) |
| Social class¶: | ||||
| I and II | 273 | 47 (17.2) | 1 | 1 |
| IIINM and IIIM | 359 | 65 (18.1) | 1.06 (0.69 to 1.64) | 0.86 (0.56 to 1.33) |
| IV and V | 171 | 27 (15.8) | 0.90 (0.52 to 1.56) | 0.70 (0.41 to 1.22) |
| Age on leaving full time education (years): | ||||
| ⩽15 | 210 | 45 (21.4) | 1 | 1 |
| 16-19 | 441 | 76 (17.2) | 0.76 (0.50 to 1.18) | 1.06 (0.68 to 1.65) |
| >19 | 200 | 23 (11.5) | 0.48 (0.27 to 0.85) | 0.87 (0.48 to 1.57) |
*
17 women with contraindications to HRT were excluded (thromboembolic disorder; breast, endometrial, and ovarian cancer; liver disease), leaving 865 subjects. Numbers sometimes add up to less than 865 because of missing values.
†
For ethnic group, hysterectomy, smoking, and age.
‡
From woman’s history.
§
Woman had history of one or more of hypertension, diabetes, high cholesterol concentration, or ischaemic heart disease.
¶
Social class was classified according to partner’s occupation, or by the woman’s if she had no partner.