Table 2.

Anti-HBs antibody responses one month after HBV challenge by pre-vaccination status (ATP Cohort for immunogenicity)

					Post challenge
		≥ 3.3 mIU/ml			≥ 10 mIU/ml			≥ 100 mIU/ml			GMC
Pre-challenge status	N	n	%	95% CI	n	%	95% CI	n	%	95% CI	value	95% CI
<3.3 mIU/ml	21	19	90.5	[69.6; 98.8]	17	81.0	[58.1; 94.6]	11	52.4	[29.8; 74.3]	85.4	[24.7; 295.0]
≥ 3.3 mIU/ml	264	264	100	[98.6; 100]	264	100	[98.6; 100]	262	99.2	[97.3; 99.9]	12524.1	[9907.2; 15832.2]
<10 mIU/ml	42	40	95.2	[83.8; 99.4]	38	90.5	[77.4; 97.3]	31	73.8	[58.0; 86.1]	249.8	[116.9; 534.1]
≥ 10 mIU/ml	243	243	100	[98.5; 100]	243	100	[98.5; 100]	242	99.6	[97.7; 100]	16010.1	[12812.2; 20006.2]
<100 mIU/ml	151	149	98.7	[95.3; 99.8]	147	97.4	[93.4; 99.3]	139	92.1	[86.5; 95.8]	2119.3	[1475.8; 3043.4]
≥ 100 mIU/ml	134	134	100	[97.3; 100]	134	100	[97.3; 100]	134	100	[97.3; 100]	42433.2	[34084.1; 52827.5]

N = number of subjects with available results. n/% = number/percentage of subjects with antibody concentrations above the specified cut-off. 95% CI = exact 95% confidence interval.