Table 2.

Univariate analysis of categorized tumour volume as a predictor of biochemical failure, and multivariate analysis of predictors of biochemical failure

Variable	Hazard ratio (95% CI)	P
Tumour volume
< 0.26	reference
0.26–0.50	1.83 (0.45–7.32)	0.393
0.51–1.00	1.44 (0.39–5.32)	0.584
1.01–2.00	2.61 (0.76–8.97)	0.127
2.01–4.00	2.52 (0.74–8.63)	0.139
> 4.00	4.3 (1.31–14.09)	0.016
Multivariate PSA, ng/mL
≤□6	reference
6.01–10	1.55 (0.90–2.50)	0.113
10.01–20	2.06 (1.12–3.77)	0.020
20.01–30	4.09 (1.49–11.2)	0.006
> 30	6.34 (2.15–18.7)	0.001
Gleason score
2–6	reference
3 + 4	2.25 (1.10–4.61)	0.026
4 + 3	3.87 (1.70–8.75)	0.001
8–10	4.34 (1.89–9.96)	0.001
SVI	1.92 (1.05–3.50)	0.034
ECE	2.01 (1.25–3.25)	0.004
SM	1.61 (1.02–2.55)	0.042
LNI	0.99 (0.62–1.68)	0.963
Tumour volume, mL
≤ 0.25	reference
0.26–0.50	1.26 (0.31–5.18)	0.748
0.51–1.00	0.80 (0.21–3.09)	0.749
1.01–2.00	1.27 (0.36–4.56)	0.710
2.01–4.00	0.79 (0.22–2.87)	0.721
> 4.00	1.11 (0.31–3.96)	0.869