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. 2009 Jun 18;30(1):157–166. doi: 10.1007/s10875-009-9311-y

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© The Author(s) 2009

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Fig. 3 — Immune recognition of ESAT-6 peptide 14 by sarcoidosis subjects according to HLA-DRB1*1101. The DRB1*1101 allele has a positive association with risk of sarcoidosis. Of 13 subjects recognizing ESAT-6 peptide 14, seven possessed the HLA-DRB1*1101 allele, compared to five of 45 non-responders (p = 0.0003). Controlling for ethnicity, this difference continued to be significant for African Americans, in which four of the seven who recognized this peptide possessed the HLA-DRB1*1101, compared to one of 15 who did not (p = 0.02). Among the Caucasian subjects, there was a trend (three out of six compared to four out of 29) toward significance (p = 0.08)