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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Pediatr Pulmonol. 2009 Oct;44(10):1003. doi: 10.1002/ppul.21092

Fig. 2. S1118F-CFTR shows impaired maturation.

Fig. 2

(A) Pulse-chase experiments to monitor the formation of mature protein over a period of 2 hours in HEK-293 cells transfected with WT-or S1118F-CFTR cDNA. The experiments were performed 4 times. (B) Quantitation of mature (Band C) and immature (Band B) protein in WT- and S1118F-CFTR from pulse-chase experiment showing impaired maturation of S1118F-CFTR. The Band B at time ‘0’ was considered as 100% for WT- and S1118F-CFTR, respectively.