Table 3.
Top 20 of 251 genes significantly regulated by strain
| Gene | Gene description | Fold change | Fold change description | Adj. p value |
|---|---|---|---|---|
| Mospd1a | Motile sperm domain containing 1 | 22.11 | F344 up vs. SD | 0.002 |
| RGD1564739 | Akin to spermatogenesis-associated glutamate (E)-r | −3.62 | F344 down vs. SD | 0.002 |
| Ly6g6e | Lymphocyte antigen 6 complex, locus G6E | 3.84 | F344 up vs. SD | 0.002 |
| Slc26a7 | Solute carrier family 26, member 7 | −4.42 | F344 down vs. SD | 0.002 |
| Hey2 | Hairy/enhancer-of-split related to YRPW motif 2 | 1.27 | F344 up vs. SD | 0.003 |
| Tap2 | Transporter 2, ATP-binding cassette, sub-family B | 5.60 | F344 up vs. SD | 0.003 |
| 10722435b | Unknown | −19.64 | F344 down vs. SD | 0.005 |
| Stk32a | Serine/threonine kinase 32A | −5.33 | F344 down vs. SD | 0.005 |
| RGD1562660 | RGD1562660 | −1.30 | F344 down vs. SD | 0.006 |
| RGD1560289 | Similar to chromosome 3 open reading frame 20 | −2.38 | F344 down vs. SD | 0.008 |
| Arsb | Arylsulfatase B | −2.50 | F344 down vs. SD | 0.008 |
| RT1-Bb | RT1 class II, locus Bb | −3.59 | F344 down vs. SD | 0.008 |
| Ly6g6d | Lymphocyte antigen 6 complex, locus G6D | 3.50 | F344 up vs. SD | 0.010 |
| 10804316b | Unknown | −1.72 | F344 down vs. SD | 0.010 |
| Oprk1 | Opioid receptor, kappa 1 | 2.00 | F344 up vs. SD | 0.010 |
| 10824257b | Unknown | 2.69 | F344 up vs. SD | 0.010 |
| Ank2 | Ankyrin 2, neuronal | −1.27 | F344 down vs. SD | 0.011 |
| 10724713b | Unknown | −1.76 | F344 down vs. SD | 0.011 |
| Fgd3 | FYVE, RhoGEF and PH domain containing 3 | 2.32 | F344 up vs. SD | 0.011 |
| 10900112b | Unknown | −3.56 | F344 down vs. SD | 0.011 |
Adjusted p value < 0.05; ± indicates overexpression or underexpression of the gene, respectively. For the entire gene list, see Supplemental Material Table S1
aGene is represented by a second exon in the array with a fold change of 17.45 and an adjusted p value of 0.002
bAffymetrix probeset ID of a gene which has not been identified