Table 5.
Genes significantly regulated (adjusted p value < 0.05) by strain in room air-exposed F344 and SD rats
| Gene | Gene description | Fold change | Fold change description | Adj. p value |
|---|---|---|---|---|
| Mospd1a | Motile sperm domain containing 1 | 22.43 | F344 RA up vs. SD RA | 0.015 |
| RGD1564739 | Akin to spermatogenesis associated glutamate (E)-r | −3.98 | F344 RA down vs. SD RA | 0.015 |
| Slc26a7 | Solute carrier family 26, member 7 | −4.10 | F344 RA down vs. SD RA | 0.022 |
| Ly6g6e | Lymphocyte antigen 6 complex, locus G6E | 3.25 | F344 RA up vs. SD RA | 0.026 |
| Tap2 | Transporter 2, ATP-binding cassette, sub-family B | 5.56 | F344 RA up vs. SD RA | 0.029 |
| Hey2 | Hairy/enhancer-of-split related with YRPW motif 2 | 1.23 | F344 RA up vs. SD RA | 0.035 |
| 10722435b | Unknown | −20.69 | F344 RA down vs. SD RA | 0.035 |
| Stk32a | Serine/threonine kinase 32A | −4.99 | F344 RA down vs. SD RA | 0.041 |
| Oprk1 | Opioid receptor, kappa 1 | 2.34 | F344 RA up vs. SD RA | 0.041 |
| Arsb | Arylsulfatase B | −2.66 | F344 RA down vs. SD RA | 0.048 |
| RGD1310110 | Similar to 3632451O06 Rik protein | −1.44 | F344 RA down vs. SD RA | 0.048 |
± indicates over- or underexpression of the gene, respectively
aGene is represented by a second exon in the array with a fold change of 17.45 and an adjusted p value of 0.015
bAffymetrix probeset ID of a gene which has not been identified