Table 1.

The random or fixed effects in the data structure for the repeated measures MT study.

Outcome Variable Y ijkln	Effect in the Variance-Component Analysis	Type of Effect	Mathematical Symbol	Index	Maximum of the Index
Mean ROI Value via Manual Segmentations	Subject	Random	S i	i = i,…, I	I = 9
	Observer	Fixed or Random	O j	j = 1,…, J	J = 2
	Time Point	Fixed or Random	T k	k = 1,…, K	K = 2
	Repetition	Fixed or Random	R l	l = 1,…, L	L = 2
	Region of Interest	Fixed	K m	m = 1,…, M	M = 12
	Interaction Terms	Generally Mixed	{S i; O j; T k; R l; K m}	{i; j; k; l; n}	Based on the Appropriate Model Specification