Table 3. Comparison of Echocardiographic Parameters at Baseline and 6-Month Follow-Up After CRT in the MR Reduction Group and the MR No-Reduction Group.
MR Reduction (n=18) |
MR No-Reduction (n=16) |
|||||
---|---|---|---|---|---|---|
Pre-CRT | Post-CRT | P | Pre-CRT | Post-CRT | P | |
MR (RV-ml) | 43±13 | 18±10 | <0.001 | 26±17* | 29±15 | 0.008 |
EDV, mL | 265±88 | 228±77 | 0.009 | 239±134 | 215±134 | 0.02 |
ESV, mL | 216±78 | 167±81 | 0.001 | 195±118 | 168±113 | 0.004 |
EF, % | 19±5 | 28±10 | <0.001 | 20±7 | 24±12 | 0.03 |
MAA, cm2 | 12.4±3.2 | 11±3.4 | <0.001 | 10.8±3.9 | 10±2.8 | 0.1 |
MAA contr, % | 3.9±0.7 | 7.8±0.5 | 0.07 | 4.2±1 | 8.8±0.7 | 0.3 |
TV, mL | 6.4±2.5 | 4.8±2.4 | <0.001 | 5±2.8 | 4.6±2.1 | 0.1 |
Leaflet closing area, cm2 | 16.9±3.8 | 14.5±4.1 | 0.008 | 14.2±4 | 13.1±3.6 | 0.2 |
Closing pressure ratio | 0.77±0.04 | 0.85±0.1 | 0.02 | 0.78±0.1 | 0.81±0.1 | 0.2 |
dP/dt, mm Hg/s | 548±227 | 867±447 | 0.02 | 519±181 | 750±264 | 0.01 |
RV indicates regurgitant volume; TV, tenting volume.
P compares pre-CRT versus post-CRT
P<0.05 (pre-CRT MR reduction versus pre-CRT MR no reduction).