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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Psychopharmacology (Berl). 2009 Apr 1;205(1):119. doi: 10.1007/s00213-009-1521-8

Figure 4.

Figure 4

Dose-response effect of amisulpride on the immobility profile of 5-HT7+/+ (□) and 5-HT7−/− (■) mice in (upper panel) the tail suspension test and (lower panel) the forced swim test. Amisulpride shows a dose-dependent antidepressant efficacy in both depression models by reducing immobility time in 5-HT7+/+ but not 5-HT7−/− mice. Values are mean ± SEM. n = 6 animals per genotype per treatment group. *p < 0.05, **p < 0.01, ***p<0.001 between the genotypes; †p < 0.05, †††p < 0.001 within a genotype compared to control; two-way ANOVA followed by Bonferroni's post-hoc test.