Fig. 3.

Comparison of the NS3₁₃₇₆ epitope in animals with and without the restricting MHC class II allele. Viral RNA was isolated from the serum of four persistently infected chimpanzees (CB0603, CB0609, CH-503, and NM1238) and amplified by PCR. Subsequent molecular cloning and sequencing were then performed to assess the sequence of the NS3₁₃₇₆ epitope in two DRB5*0310-positive chimpanzees (CB0609 and CH-503; highlighted) and two chimpanzees (NM1238 and CB0603) that did not express this restricting MHC class II allele. The frequencies of each identified sequence are indicated on the right.