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Population spike amplitude recorded from the CA1 area of adult P61–65 slices before, during, and after perfusion of 2 concentrations of ISO (A and B). The 10-min ISO perfusion period is indicated by the open bar starting at the 10-min mark. Insets show exemplar population spikes immediately before and 20-min after the start of ISO perfusion. Values are means ± SEM with the number of slices shown in each panel. Each slice was subjected to only a single ISO concentration.
