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. 2010 Feb 16;5(2):e9234. doi: 10.1371/journal.pone.0009234

Figure 4. AFM analysis of α-syn aggregation in the presence or absence of both ThT and DOP.

Figure 4

AFM height images were acquired from assay end products, which had been deposited onto freshly cleaved mica surfaces after 100 hours of incubation. The presence or absence of ThT revealed no observable effect upon either the formation or morphology of α-syn fibrils when assay was run with α syn alone, (A) +ThT, (D)–ThT. The inhibitory effect of DOP on the α syn fibrillization was clearly observed when the assay was run in the presence of DOP. (B, C, E, F). Moreover, the presence (B, C) or absence (E, F) of ThT did not show any effect upon the inhibitory action of DOP on α-syn fibrillization.