Table 1.

Estimates of evolutionary rates from FIV and HIV-1 studies

Lentivirus and region	Rate estimate (×10−3 substitutions per site per year)	Reference
FIV-Fca V1-V2 env	3.4	(Greene et al., 1993)
FIV-Fca V3-V6 env	3.1–6.6§	(Hayward, 2009)
FIV-Pco V4-V5 env	1–3	(Biek et al., 2003)
HIV-1 gp160 env	2.4	(Korber et al., 2000)
HIV-1 C2-V5	10	(Shankarappa et al., 1999)
HIV-1 V3 env	6.7	(Leitner and Albert, 1999)
HIV-1 V3 env	8.7	(Zhang et al., 1997)

^§95 % highest posterior density (HPD) for each cat is 2.2–4.1, 5.0–8.4, and 3.3–9.2