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. Author manuscript; available in PMC: 2011 Feb 20.
Published in final edited form as: Virology. 2009 Dec 3;397(2):260. doi: 10.1016/j.virol.2009.08.043

Figure 4. FTY720 does not reduce viremia or virus titer in tissues of mice persistently infected with LCMV-Cl 13.

Figure 4

(A and B) Mice were infected i.v. with 2×106 PFU LCMV-Cl 13. Mice were treated with vehicle (VEH, shaded squares), 5 (shaded circles) or 50 µg/kg (shaded triangles) of FTY720 on days 30, 31 and 32 post-infection. (A) Plaque assays of serum samples from all cohorts display no significant difference in viral titers. n=4 mice per group; data is represented as average ± SEM. (B) Tissues harvested on day 62 post infection were used for determination of viral titer by plaque assay. Differences between experimental groups are not statistically significant. Circles represent individual mice while bars indicate the group average. Experiments were replicated 3 times by two independent groups, which obtained similar results.