Table 3. Open field activity and exploration on postnatal days (PNDs) 16/17 and 20/21.
Data are mean ± SEM for a 10-min test.
| PND 16/17 | PND 21/22 | Within-sex repeated measures ANOVAa | ||||
|---|---|---|---|---|---|---|
| C57 | C58 | C57 | C58 | Main effect of strain | Strain × age interaction | |
| Distance traveled (cm) | ||||||
| Males | 269±104 | 1266±378* | 1482±92 | 3657±346* | F=36.79, p<0.0001 | F=9.91, p=0.0066 |
| Females | 139±29 | 1585±414* | 1346±59 | 3548±323* | F=47.67, p<0.0001 | F=2.76, p=0.1204 |
| Rearing | ||||||
| Males | 3.4±2 | 26.5±9* | 27.8±3 | 71.6±6* | F=38.35, p<0.0001 | F=5.0, p=0.0410 |
| Females | 0.6±0.5 | 35.9±9* | 23.9±2 | 63.4±6* | F=59.06, p<0.0001 | F=0.17, p=0.6869 |
| Jumps | ||||||
| Males | 0.52±0.5 | 5.2±3 | 1.1±1 | 22.3±5* | F=33.65, p<0.0001 | F=6.9, p=0.0191 |
| Females | 0±0 | 9.1±6 | 0.2±0.1 | 32.9±7* | F=23.22, p=0.0003 | F=8.07, p=0.0139 |
| Groom (sec) | ||||||
| Males | 21±8 | 110±24* | 159±14 | 125±20 | F=6.05, p=0.0265 | F=9.82, p=0.0068 |
| Females | 19±7 | 92±19* | 168±18 | 135±16 | F=1.72, p=0.2126 | F=11.69, p=0.0046 |
| Center time (sec) | ||||||
| Males | 5.2±4 | 28.4±18 | 13.0±2 | 22.5±6 | F=4.37, p=0.054 | F=0.6, p=0.4521 |
| Females | 0.2±0.1 | 16.7±9 | 10.1±2 | 20.9±4* | F=8.02, p=0.0141 | F=0.48, p=0.5012 |
| Corner time (sec) | ||||||
| Males | 556±18 | 222±50* | 281±26 | 167±17* | F=62.73, p<0.0001 | F=13.56, p=0.0022 |
| Females | 583±8 | 377±43* | 309±23 | 159±21* | F=33.14, p<0.0001 | F=2.04, p=0.1766 |
a
Degrees of freedom for statistical comparisons = (1,15) for males and (1,13) for females.
*
p<0.05 vs. same sex C57.