. Author manuscript; available in PMC: 2011 Feb 28.

Published in final edited form as: Stat Med. 2010 Feb 28;29(5):546–557. doi: 10.1002/sim.3798

Table 1.

Baseline characteristics of study subjects and changes in modified rankin scale over time (we show the mean (standard deviation) and the frequency (%) for modified rankin scale and the disease subtypes, respectively)

	rt-PA group (n = 292)	Placebo group (n = 295)	p-value
Disease subtypes
small vessel	31 (10.62%)	30 (10.17%)
large vessel or cardioembolic stroke	181 (61.99%)	184 (62.37%)	0.9804^a
Modified rankin scale
modified rankin scale prior onset	0.27 (0.73)	0.29 (0.80)	0.9872^b
modified rankin scale (7–10 days)	2.55 (1.20)	2.90 (1.07)	0.0006^b
modified rankin scale (3 months)	1.97 (1.07)	2.27 (1.02)	0.0017^b
modified rankin scale (6 months)	1.91 (1.04)	2.18 (1.04)	0.0060^b
modified rankin scale (12 months)	1.81 (1.01)	2.13 (1.04)	0.0015^b

The p-values are calculated using Chi-square test

The p-values are calculated using Wilcoxon rank-sum test