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. Author manuscript; available in PMC: 2011 Feb 28.
Published in final edited form as: Stat Med. 2010 Feb 28;29(5):546–557. doi: 10.1002/sim.3798

Table 2.

Results from the joint analysis for the NINDS study

Estimate (SE)
Longitudinal outcome
proportional odds (PO)
(cumulative prob of Yk, k = 1, 2, 3)
group 1.48 (0.33)
modified Rankin scale prior onset −1.67 (0.27)
time3 2.12 (0.20)
time6 2.27 (0.20)
time12 2.45 (0.22)
small vessel × group −0.74 (1.26)
large vessel or cardioembolic stroke × group −2.27 (0.76)
partial PO (cumulative prob of Y ≤ 1)
small vessel 3.49 (0.68)
large vessel or cardioembolic stroke −1.04 (0.44)
partial PO (cumulative prob of Y ≤ 2)
small vessel 3.77 (0.68)
large vessel or cardioembolic stroke −1.36 (0.39)
partial PO (cumulative prob of Y ≤ 3)
small vessel 6.14 (1.15)
large vessel or cardioembolic stroke −0.64 (0.49)
Cause-specific hazards
Risk 1: dropout
group 0.23 (0.47)
modified Rankin scale prior onset 0.06 (0.42)
small vessel 0.55 (0.57)
large vessel −0.29 (0.51)
small vessel × group 0.04 (1.14)
large vessel or cardioembolic stroke 0.30 (1.02)
Risk 2: death or remaining in severe disability
group −0.46 (0.27)
modified Rankin scale prior onset 0.53 (0.17)
small vessel −2.07 (0.79)
large vessel 0.37 (0.27)
small vessel × group 0.35 (1.49)
large vessel or cardioembolic stroke 0.81 (0.54)
Random effects
σb2 34.66 (3.94)
σu2 0.51 (0.07)
ρ bu −0.997 (0.19)
ν 2 3.12 (0.51)

p-value < 0.05