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. Author manuscript; available in PMC: 2011 Feb 28.
Published in final edited form as: Stat Med. 2010 Feb 28;29(5):546–557. doi: 10.1002/sim.3798

Table 3.

Comparison of the joint model and the separate analysis of the longitudinal outcome (n = 200)

Separate Joint

Parameter True Bias SE CP Bias SE CP MSES/MSEJ
Longitudinal
 Fixed effects
β 1 −1 0.322 0.301 0.795 −0.020 0.155 0.970 7.954
β 2 1.5 0.030 0.352 0.940 0.014 0.294 0.960 1.441
β 3 0.8 −0.216 0.528 0.935 0.039 0.287 0.990 3.879
α 2 0 −0.023 0.285 0.950 −0.008 0.236 0.975 1.466
θ 1 −0.5 0.017 0.161 0.960 −0.010 0.165 0.950 0.959
θ 2 1 0.023 0.178 0.955 0.015 0.153 0.950 1.363
 Random effects
σb2 1 −0.059 0.589 0.900 0.021 0.346 0.955 2.916
Survival
 Fixed effects
γ 11 0.8 −0.015 0.152 0.950 0.062 0.163 0.965 0.767
γ 12 −1 0.014 0.308 0.950 −0.079 0.297 0.955 1.006
γ 21 0.5 0.009 0.170 0.970 0.041 0.159 0.965 1.075
γ 22 −1 −0.024 0.301 0.970 −0.072 0.269 0.975 1.176
 Random effects
ν 2 0.5 −0.192 0.894 0.985 0.044 0.419 0.960 4.711
σu2 0.5 −0.112 0.418 0.910 0.203 0.473 0.930 0.707
Covariance
ρ bu −0.9 0.048 0.127 0.990

Note: Large bias and poor CP are highlighted in boldface.