Fig. (1). Different thiazolidinediones have only partially overlapping gene expression profiles.
The total number of genes regulated by a particular TZD is shown next to its name. The number of genes uniquely regulated by a particular TZD is contained in the non-overlapping regions of each circle. The numbers of genes similarly regulated by two or three TZDs are contained in the overlapping regions of the circles [57]. (Reprinted from Biochem Biophys Res Commun, 364(3), Sears DD, Hsiao A, Ofrecio JM, Chapman J, He W, Olefsky JM, Selective modulation of promoter recruitment and transcriptional activity of PPARgamma, 515-521, Copyright © 2007, with permission from Elsevier).