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AE1 E758K mediates GPA-dependent [14C]oxalate uptake. A: [14C]oxalate uptake by Xenopus oocytes expressing wild-type AE1 or AE1 mutant E758K with coexpressed GPA at bath pH 7.4 or 5.5. *and gray bar indicate P < 0.05 compared to pH 7.4 (Student‘s unpaired t-test). B: GPA-dependence of AE1 E758K-mediated [14C]oxalate uptake. *and black bar indicate P < 0.05 vs. absence of GPA (gray bar; Student's unpaired t-test). Values are H2O-corrected means ± SE for (n) oocytes.
