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Rhythmicity in measures of colonic motility in WT mice persists in constant darkness. A: stool output in WT mice (n = 3). B: total stool output during light (ZT0–12) and dark cycle (ZT12–0). C: colonic circular muscle contractility in WT mice at ZT1 (n = 4) and ZT13 (n = 4) expressed as AUC (g·s) ± SE. D: intracolonic pressure changes in a single WT mouse under constant darkness.
