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Pregnancy induced liver growth and serum bile acid concentrations in long-term cholate-fed, Fxr−/− and Pxr−/− mice. A: total serum bile acids. B: liver weight. Results are shown as means ± SE (n = 6 or more). Two-way ANOVA, *P < 0.05 compared with wild-type (WT), #P < 0.05 compared with nonpregnant animals.
