Table 3.
Effect of luminal bafilomycin A1 on βi, pHi recovery, and JH in A- and B-type ICs of the CCD in the presence of EIPA
| N(n) | βi | pHi Recovery, U/min | JH, mM H/min | |
|---|---|---|---|---|
| A-type ICs | ||||
| Control | 18(5) | 72.99 ± 3.78 | 0.31 ± 0.02 | 23.03 ± 1.85 |
| Luminal BafA1 | 26(5) | 62.59 ± 5.26 | 0.21 ± 0.04† | 9.48 ± 0.98* |
| B-type ICs | ||||
| Control | 36(4) | 58.21 ± 2.97 | 0.30 ± 0.03 | 16.16 ± 1.30 |
| Luminal BafA1 | 22(3) | 55.82 ± 4.84 | 0.11 ± 0.02* | 6.00 ± 0.96* |
Values are means ± SE; N, number of cells; n, number of tubules. BafA1, bafilomycin A1. All comparisons are within the same cell type.
*
P < 0.01 vs. control.
†
P < 0.05 vs. control.