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. 2010 Feb 15;207(2):353–363. doi: 10.1084/jem.20091738

Figure 6.

Figure 6.

Lack of IL-21 does not alter Salmonella pathogen clearance or production of anti-Salmonella humoral immunity. (A) ELISA analysis of the titers of Salmonella-specific IgM, IgG1, IgG2ab, IgG2b, and IgG3 in sera from Il21+/+(white bars) and Il21−/− (black bars) mice 12 d after Salmonella infection. (B and C) Dot plots of spleen weights (B) and the number of bacteria per liver (C) in Il21+/+ and Il21−/− mice 12 d after infection with Salmonella. Data are representative of two independent experiments. Each symbol represents one mouse and tops of bars are drawn through the median values. nd, not detected.