Figure 4.
Fate-mapping analysis of Rorc-expressing precursors. (A) Frequency of YFP+ cells in gated CD3−NKp46+ cells from small intestinal (SI) LPLs and intraepithelial (IEL) cells. One representative experiment out of five is shown. Means of 51 ± 18% and 18 ± 12% YFP+ cells were detected in the LPL and intraepithelial compartments, respectively. (B) NK1.1 versus CD127 expression on YFP+ versus YFP− subsets of intestinal CD3−NKp46+ small intestinal LPL and intraepithelial cells. (C) Frequency of YFP+ cells in gated CD3−NK1.1+ cells from the indicated organs/tissues. Results indicate frequencies from one representative experiment out of five performed.