Table 1.
Pathological assessment of perivenous demyelination cohort
|
Pattern/location of demyelination |
Cortical |
Other |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Case | Sample | PVD | CD | WM | GM | Subpial | CMA | Haemorrhage | Necrosis | Meningitis |
| 1 | A | + | + | + | + | + | + | - | - | + |
| 2 | A | + | – | + | + | – | + | + | + | + |
| 3 | B/A | + | – | + | + | – | + | + | + | + |
| 4 | B/A | + | – | + | + | + | + | + | + | + |
| 5 | B | + | – | + | – | – | – | + | + | – |
| 6 | B | + | – | + | NA | NA | NA | – | – | NA |
| 7 | B | + | – | + | NA | NA | NA | – | – | NA |
| 8 | B | + | – | + | + | + | + | + | + | + |
| 9 | B | + | – | + | – | – | – | – | – | – |
| 10 | B | + | – | + | – | – | – | + | + | + |
| 11 | B | + | – | + | – | – | – | – | – | – |
| 12 | B | + | + | + | + | – | + | – | – | + |
| 13 | B | + | + | + | NA | NA | NA | – | – | NA |
A = autopsy; B = biopsy; PVD = perivenous demyelination; CD = confluent demyelination; WM = white matter; GM = grey matter; CMA = cortical migroglial activation; NA = adequate tissue not available.