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Tension-pCa relationship of myofiber preparations from Ntg and TPM1κ Tg hearts. A, Tension-pCa relationship with a sarcomeric length set at 2.0 μm. B, Tension-pCa relationship before and after treatment with NEM-S1. C, Expanded scale of tension generated at low Ca2+ concentrations which enhances recruitment of crossbridges by NEM-S1.
