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. Author manuscript; available in PMC: 2011 Jan 28.
Published in final edited form as: Neuron. 2010 Jan 28;65(2):257. doi: 10.1016/j.neuron.2009.12.002

Figure 6. mPFC theta power is increased specifically in the safe zones of the anxiogenic arenas.

Figure 6

(A) Theta power increases in the mPFC, vHPC and dHPC during navigation of the periphery (dark red) and center (bright red) of the open field. (B) Theta power increase in each area during navigation of the closed arms (dark blue), open arms (medium blue), and center (light blue) of the elevated plus maze. n=18 and 12 for the open field and EPM, respectively. All data are from epochs in which animals were running consistently in the 7-15 cm/s speed range. Fold increases are relative to theta power in the familiar arena exposure on the same day. Error bars are ± s.e.m. *p<0.05, for a paired Wilcoxon’s signed rank test.