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. Author manuscript; available in PMC: 2011 Jan 28.
Published in final edited form as: Neuron. 2010 Jan 28;65(2):246. doi: 10.1016/j.neuron.2010.01.002

Figure 7. Dark rearing from birth delays the critical period of binocular matching.

Figure 7

(A) Mice were reared in constant darkness (DD) from P0 to P31 and then in normal light-dark (LD) cycle. They were recorded immediately or 6–7 days after the long-term dark rearing (LTDR-0 and LTDR-6/7, respectively). (B) Distribution of difference in preferred orientations through the two eyes in LTDR-0 mice. (C) Cumulative distribution of ΔO for LTDR-0 (56 cells, 6 mice) and LTDR-6/7 (58 cells, 4 mice). The ΔO distributions of normal adult control (solid gray line) and random matching (dotted gray line) are shown for comparison. (D) Mean ΔO of all groups, for all cells, selective and highly selective cells. (E–F) Mean tuning curves through contralateral (E) and ipsilateral (F) eyes for mice immediately after dark-rearing (LTDR-0) and age-matched controls (P31–P36).