Table 4.
Comparison between scleroderma subtypes, data are expressed as mean ± SD
| Diffuse-type SSc Scleroderma (n = 11) |
Limited-type Scleroderma (n = 11) |
P value | |
|---|---|---|---|
| Systolic PAP, mmHg | 23 ± 6.5 | 23 ± 2.7 | 0.562 |
| DLCO, % | 56.6 ± 16.5 | 70.1 ± 13.8 | 0.065 |
| RVOT 1, mm | 29.1 ± 4.3 | 29.3 ± 3.9 | 0.847 |
| RVOT 2, mm | 20.5 ± 2.5 | 18.7 ± 2.3 | 0.114 |
| RV-Diameter, mm | 31.2 ± 2.9 | 31.4 ± 4.2 | 0.949 |
| RVEF, % | 49.9 ± 8.5 | 52.4 ± 8.8 | 0.562 |
| TAPSE, mm | 22.6 ± 4.6 | 23.8 ± 3.8 | 0.591 |
| Sm, cm/s | 11.6 ± 2.7 | 11.5 ± 2.1 | 1.000 |
| Em, cm/s | 10.3 ± 3 | 12.3 ± 3.7 | 0.243 |
| Am, cm/s | 13.4 ± 3.9 | 14.7 ± 2.9 | 0.300 |
| IVV, cm/s | 9.7 ± 3.3 | 10.9 ± 2.7 | 0.401 |
| AT, ms | 44.3 ± 14.3 | 45 ± 11.5 | 0.898 |
| IVRT, ms | 67 ± 37.8 | 58 ± 32.3 | 0.606 |
| IVA, m/s2 | 2.2 ± 0.4 | 2.4 ± 0.4 | 0.171 |
| MPI | 0.61 ± 0.28 | 0.49 ± 0.12 | 0.365 |
| 2D-Strain basal, % | -19.9 ± 7.7 | -23.1 ± 10 | 0.661 |
| 2D-Strain medial, % | -21.2 ± 6.9 | -23.6 ± 9.2 | 0.604 |
| 2D-Strain apical, % | -21.8 ± 9.9 | -24.4 ± 7.6 | 0.656 |
| DTI-Strain basal, % | -24.5 ± 8.5 | -24.1 ± 6.2 | 0.847 |
| DTI-Strain medial, % | -22.7 ± 7.9 | -30.8 ± 10.7 | 0.173 |
| DTI-Strain apical; % | -25.2 ± 7.6 | -25.1 ± 8.5 | 0.797 |
PAP - pulmonary artery pressure, DLCO - diffusing capacity of the lung for carbon monoxide, RVOT - right ventricular outflow tract, RV-diameter - right ventricular diameter, RVEF - right ventricular ejection fraction, TAPSE - tricuspid annular plane systolic excursion, Sm - peak systolic myocardial velocity, Em - early diastolic myocardial velocity, Am - late diastolic myocardial velocity, IVV - isovolumetric myocardial velocity, AT - acceleration time, IVRT - isovolumetric relaxation time, IVA - isovolumetric acceleration, MPI - myocardial performance index