Table 2.
Gene | Position (#of mutations) |
---|---|
BRAF(766 aa) | 464(1), 466(2), 469(4), 581(1), 596(2), 597(2), 600(60), 601(2) |
KRAS(188 aa) |
12(99), 13(32), 22(1), 23(1), 61(6), 117(1), 146(10) |
CTNNB1 (781 aa) | 6(1), 33(3), 34(2), 37(3), 41(2), 45(2) |
PIK3CA(1068 aa) |
88(3), 111(3), 118(1), 124(1), 345(1), 449(1), 453(1), 539(1), 542(5), 545(20), 546(2), 549(1), 1023(1), 1025(1), 1047(21), 1049(1), 1066(1) |
The number of mutations for each position is shown in parenthesis, positions within clusters from Table 1 are highlighted in bold, and CpG positions are underlined.