Table 2.

Univariate analysis of in-hospital-mortality: patient characteristics and etiology.

Variable		Alive N = 497	Deaths N = 208	RR	95% CI	p
Age (years)	Mean ± SD	51.6 ± 17	58.8 ± 16	-	-	<0.001
Gender	Male	345 (71)	141 (29)	1.07	0.76-1.52	0.367
	Female	152 (69.4)	67 (30.6)
Period	1984-1995	196 (74.5)	67 (25.5)	1.25	0.97-1.60	0.070
	1996-2006	301 (68.1)	141 (31.9)
Hospital	Tertiary	451 (69.3)	200(30.7)	2.07	1.08-3.96	0.008
	Community	46 (85.2)	8 (14.8)
Nosocomial	Yes	55 (53.4)	48 (46.6)	1.75	1.37-2.24	<0.001
	No	442 (73.4)	160 (26.6)
Comorbidity	Yes	259 (64.4)	143 (35.6)	1.65	1.28-2.13	<0.001
	No	238 (78.8)	65 (21.5)
Charlson's index	Mean ± SD	1.56 ±	2,50 ±			<0.001
		2.15	2.42
Diabetes mellitus	Yes	24 (68.8)	11 (31.4)	1.06	0.64-1.76	0.464
	No	473 (70.6)	197 (29.4)
Chronic renal insufficiency	Yes	14 (58.3)	10 (41.7)	1.43	0.88-2.33	0.184
	No	483 (70.9)	198 (29.1)
Chronic liver	Yes	17 (53.1)	15 (46.9)	1.63	1.10-2.40	0.027
Disease	No	480 (71,3)	193 (28,7)
Valve involved	Aortic	223 (71.9)	118 (29.3)	1.02	0.81-1.28	0.456
	Mitral	274 (69.3)	90 (29.1)
>1 valve involved	Yes	49 (64.5)	27 (35.5)	1.23	0.89-1.71	0.223
	No	448 (71,2)	181 (28,8)
Valve type	Prosthetic	104 (60.8)	67 (39.2)	1.48	1.17-1.87	0.001
	Native	393 (73.6)	141 (26.4)
Prosthetic type	Early	33 (47.8)	36 (52.2)	1.93	1.48-2.50	<0.001
	Late	464 (73)	172 (27)
S. aureus	Yes	70 (51.1)	67 (48.7)	1.96	1.57-2.46	<0.001
	No	427 (75.2)	141 (24.8)
S. viridans group	Yes	140 (89.7)	16 (10.3)	0.29	0.18-0.47	<0.001
	No	357 (65)	192 (35)
Coagulase-negative Staphylococci	Yes	64 (62.7)	38 (37.3)	1.32	0.99-1.75	0.040
	No	433 (71.8)	170 (28.2)
Enterococcus spp.	Yes	52 (66.7)	26 (33.3)	1.14	0.1-1.60	0.254
	No	445 (71)	182 (29)
S. agalactiae	Yes	7 (46.7)	8 (53.3)	1.84	1.12-2.99	0.044
	No	490 (71)	200 (29)
Fungal	Yes	2 (22.2)	7 (77.8)	2.69	1.86-3.89	0.004
	No	495 (71.1)	301 (28.9)

Data are expressed as number of cases (%) except when indicated.