Table 2.
Number of rejection episodes before, during and after tTLI
| Patient | Rejection episodes before tTLI* | Rejection episodes during tTLI* | Rejection episodes after tTLI* | Time to first subsequent rejection episode (months) | Severe Infections during tTLI | Current status |
|---|---|---|---|---|---|---|
| 1 | 7 | 1 | 1 | 31 | HZ | alive |
| 2 | 5 | 2 | 1 | 25 | none | alive |
| 3 | 5 | 0 | 1 | 5 | none | alive |
| 4 | 12 | 0 | 0 | n.a. | none | dead# |
| 5 | 3 | 0 | 2 | 77 | US, PJP | alive+ |
| 6 | 4 | 1 | 6 | 29 | none | alive |
| 7 | 5 | 0 | 1 | 31 | none | alive |
Abbreviations: tTLI = tailored total lymphoid irradiation; n.a. = not applicable; HZ = generalized herpes zoster; US = urosepsis; PJP = pneumocystis jirovecii pneumonia; * Rejection episodes were defined as a rejection of ≥ IIIA according to the International Society for Heart and Lung Transplantation (ISHLT) criteria; # patient died because of graft coronary artery disease; + patient experienced a post-transplant lymphoproliferative disorder.