Table 1.
NPD1, RvD1 and RvE1 dose-dependent inhibition of apoptosis induced by oxidative stress in RPE cells
Treatment | Dose (nM) | % Inhibition |
---|---|---|
NPD1 | 10 | 2.6 |
25 | 44.8 | |
50 | 92.4 | |
RvD1 | 10 | 0.0 |
25 | 4.8 | |
50 | 38.4 | |
RvE1 | 10 | 0.0 |
25 | 3.2 | |
50 | 29.2 |
The 72-h grown ARPE-19 cells in six-well plates were serum starved for 8 h. Oxidative stress was introduced by H2O2/TNF-α as before [2]. Stressed cells were challenged with NPD1, RvD1, and RvE1 at different concentrations as indicated for 15 h. Results are averages of five repeated points each from three independent experiments.