Table 1.
Control | Hypertrophy | P Value | |
---|---|---|---|
Heart rate, beats/min | 105±9 | 130±12 | <0.05 |
LVPmax, mmHg | 113±7 | 117±5 | NS |
LVP at MVO, mmHg | 4±2 | 19±4 | <0.01 |
LVEDP, mmHg | 5±2 | 21±4 | <0.05 |
Diastolic filling, ms | 304±33 | 244±42 | NS |
dP/dtmax, mmHg/s | 2,476±203 | 2,330±216 | NS |
dP/dtmin, mmHg/s | −2,466±190 | −2,076±166 | <0.05 |
τ, ms | 32±2 | 43±1 | <0.05 |
Values are means ± SE; n = 6. LVPmax, maximum left ventricular pressure (LVP); MVO, mitral valve opening; LVEDP, left ventricular end-diastolic pressure; dP/dtmax and dP/dtmin, peak positive and negative dP/dt, respectively; τ, time constant of isovolumic LVP decline; NS, not significant.