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. Author manuscript; available in PMC: 2011 Feb 23.
Published in final edited form as: Biochemistry. 2010 Feb 23;49(7):1507. doi: 10.1021/bi9016846

FIGURE 6.

FIGURE 6

Increased DsRed expression following treatments to reverse epigenetic modifications of genomic DNA. FACS analyses of clones 51-11 and 51-9 following treatment with 5-Aza-2′-deoxycytidine (5-aza) to inhibit DNA methylation (A, left panel) or with Trichostatin A (TSA) to block histone deacetylation of the chromatin (A, right panel) showed the increase of DsRed expression. The data (mean ± 1 SD) represent results from three independently treated cultures with each reagent. The clones and the number of treatment days with each chemical reagent are indicated below the horizontal axis. (B) Representative FACS analyses are shown that were performed after treatment for 6 days with either 5-aza or TSA, and the percentage of DsRed+ cells is indicated in the upper left of each plot.