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. Author manuscript; available in PMC: 2011 Feb 15.
Published in final edited form as: Cancer Res. 2010 Feb 9;70(4):1323. doi: 10.1158/0008-5472.CAN-09-1474

Figure 3. Ets2 represses expression of anti-angiogenic genes in TAMs.

Figure 3

ChIP analysis of the Ets-binding sites in Thbs1 (A, distal Ets site), Thbs2 (B), Timp3 (C) and Timp1 (D) promoters from YFP+ cells extracted from the lung following tail-vein injection of Met-1 cells. ChIP was performed with α-ETS2 and α-HDAC1 antibodies and rabbit IgG control, as indicated. Subsequently, qPCR was performed on the immunoprecipitated chromatin. Results from two independent experiments are represented as mean of relative enrichment of the amplified chromatin ± standard errors of the mean (error bars)