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Size exclusion chromatographic (SEC) analysis of SAM-I and P4-P6 domain. Gel-filtration elution profiles for folded RNAs. Vertical axis is the mAu at 280 nm. (A) SAM-I RNA before purification (broken green line) and after SAXS of the purified RNA (red line); (B) P4-P6 domain (solid green line). Arrows mark regions of heterogeneity.
